Protein name:
C4b-binding protein (C4bp) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homoheptamer; not covalently linked. Mouse lacks the beta chain of C4BP.
Function:
Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with serum amyloid P component.
Subcellular Location:
Secreted
Protein Attributes:
50:
MCAKQQQTLL | PTRAAHGRLH | RNRDAVAWPF | STLCRVSGPT | LFQMTFTAAL |
100:
WVAVFGKCGP | PPAIPNALPA | SDVNRTDFES | HTTLKYECLP | GYGRGISRMM |
150:
VYCKPSGEWE | ISVSCAKKHC | RNPGYLDNGY | VNGETITFGS | QIEFSCQEGF |
200:
ILVGSSTSSC | EVRGKGVAWS | NPFPECVIVK | CGPPPDISNG | KHSGTEDFYP |
250:
YNHGISYTCD | PGFRLVGSPF | IGCTVVNKTV | PVWSSSPPTC | EKIICSQPNI |
300:
LHGVIVSGYK | ATYTHRDSVR | LACLNGTVLR | GRHVIECQGN | GNWSSLPTCE |
350:
FDCDLPPAIV | NGYYTSMVYS | KITLVTYECD | KGYRLVGKAI | ISCSFSKWKG |
400:
TAPQCKALCQ | KPEVGNGTLS | DEKDQYVESE | NVTIQCDSGF | AMLGSQSISC |
450:
SESGTWYPEV | PRCEQEASED | LKPALTGNKT | MQYVPNSHDV | KMALEIYKLT |
469:
LEVELLQLQI | QKEKHTEAH
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Bovine
Polyclonal Antibody for Mouse C4bp
Polyclonal Antibody for Mouse C4bp
Polyclonal Antibody for Mouse C4bp
Polyclonal Antibody for Mouse C4bp
Monoclonal Antibody for Mouse C4bp
Monoclonal Antibody for Mouse C4bp
Monoclonal Antibody for Mouse C4bp
Monoclonal Antibody for Mouse C4bp
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
"The transcriptional landscape of the mammalian genome."
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Science309:1559-1563(2005)
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Liver .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
FVB/N .
tissue :
Liver .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-275
strain :
C57BL/6 .
tissue :
Plasma .